HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,2,3,6-Tetrahydropyridine → 1-(6-(2-Butynyloxy)pyrimidin-4-yl)-1,2,3,6-tetrahydropyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,2,3,6-Tetrahydropyridine | HCID 12750 | — |
| Reactant | 4-(2-Butynyloxy)-6-chloropyrimidine | HCID 12137602 | — |
| Product | 1-(6-(2-Butynyloxy)pyrimidin-4-yl)-1,2,3,6-tetrahydropyridine | HCID 57819812 | 100.9% |
Reaction Steps
0.3 g of 4-chloro-6-(2-butynyloxy)pyrimidine and 0.41 g of 1,2,3,6-tetrahydropyridine were mixed and left for 2 hours at room temperature. The reaction mixture was subjected to silica gel column chromatography to obtain 0.38 g of 1-(6-(2-butynyloxy)pyrimidin-4-yl)-1,2,3,6-tetrahydropyridine (hereinafter, referred to as Compound (54)).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07732448B2 |
| Source dataset | uspto-grants-2010_06 |
| ORD ID | ord-d976352f2ebb4c96abede001169aa40a |
| Source note | uspto-grants-2010_06 |