Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sulfuric Acid → Butyl 1,6-dihydro-6-oxo-3-pyridazinecarboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sulfuric Acid | HCID 1118 | — |
| 반응물 | Butyl Acetate | HCID 31272 | — |
| 반응물 | 6-Hydroxypyridazine-3-carboxylic Acid | HCID 305970 | — |
| 용매 | 1-Butanol | HCID 263 | — |
| 생성물 | Butyl 1,6-dihydro-6-oxo-3-pyridazinecarboxylate | HCID 12346430 | 79.6% |
반응 단계
A mixture of 6-oxo-1,6-dihydropyridazine-3-carboxylic acid (117.24 g) [Ref: British Patent 856, 409], n-butyl acetate (293 ml), n-butanol (410 ml) and conc. H2SO4 (5.9 ml) was heated at reflux for 1 hour. The solvent was evaporated and the residue washed with n-butyl acetate to give n-butyl 6-oxo-1,6-dihydropyridazine-3-carboxylate (130.6 g, 79.6% yield), mpt 79°-8° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05843942 |
| 출처 데이터셋 | uspto-grants-1998_12 |
| ORD ID | ord-b7c6fe4f533846a2811c09e57cbf908f |
| 출처 메모 | uspto-grants-1998_12 |