HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1455954Generated: October 26, 2026
Hydroxyamine hydrochloride → 2-Benzyloxy-5-bromobenzaldehyde oxime
https://huagongshe.com/reaction/1455954
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydroxyamine hydrochloride | HCID 443297 | — |
| Reactant | 2-(Benzyloxy)-5-bromobenzaldehyde | HCID 733087 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | 2-Benzyloxy-5-bromobenzaldehyde oxime | HCID 20985908 | 142.6% |
Reaction Steps
A mixture of 2-benzyloxy-5-bromobenzaldehyde (20 g) and hydroxylamine hydrochloride (9.55 g) in pyridine (50 ml) was heated at 75° C. for 45 minutes. The solvent was evaporated and the residue purified by chromatography, eluting with dichloromethane, to give 2-benzyloxy-5-bromobenzaldehyde oxime (30 g) (mp 132°-134° C.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US05843942 |
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| Source dataset | uspto-grants-1998_12 |
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| ORD ID | ord-e0121d8b0f954d999e45068867b2cfb8 |
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| Source note | uspto-grants-1998_12 |
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