Carbon tetrabromide → HCID 22105537, compound

Participants

Reaction Conditions

Reaction Steps

1-(2-Benzyloxy-5-bromophenyl)-ethanol (3.69 g) was dissolved in dichloromethane (80 mL) and cooled to 0° C. under argon. Triphenyl phosphine 93.47 g) was added followed by carbon tetrabromide (7.36 g) and stirred for eighteen hours, allowing to warm to ambient temperature. After removal of solvent the residue was purified by MPLC (eluting 50% dichloromethane, 50% hexane, silica) to give 1-(2-benzyloxy-5-bromophenyl)ethyl bromide (2.9 g) which was used immediately without further purification.

Provenance & Evidence