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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1455981Generated: October 26, 2026

Water → 2-(Benzyloxy)-4-bromobenzaldehyde

https://huagongshe.com/reaction/1455981

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantBenzyl BromideHCID 7498—
ReactantPotassium CarbonateHCID 11430—
Reactant4-Bromo-2-hydroxybenzaldehydeHCID 4066019—
SolventDimethylformamideHCID 6228—
Product2-(Benzyloxy)-4-bromobenzaldehydeHCID 15673062—

Reaction Steps

Benzyl bromide (1.35 ml) was added to a mixture of 4-bromo-2-hydroxybenzaldehyde (2.07 g) and potassium carbonate (1.38 g) in DMF (20 ml) and the mixture was stirred at ambient temperature for 10 hours. The reaction mixture was poured into water (50 ml) to give 2-benzyloxy-4-bromobenzaldehyde as a solid which was filtered and dried, yield 2.88 g. The material was used in subsequent reactions without purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05843942
Source datasetuspto-grants-1998_12
ORD IDord-5240495585e14aebba79cf7818d27b88
Source noteuspto-grants-1998_12