Benzoic acid, 4-(ethylamino)-, ethyl ester → HCID 22105552, compound

HRID 1455992Notes

Reaction equation

HRID 1455992 reaction equation
[CH2:1]([O:8][C:9]1[CH:13]=[CH:12][S:11][C:10]=1[C:14]([OH:16])=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH2:17]([NH:19][C:20]1[CH:30]=[CH:29][C:23]([C:24]([O:26][CH2:27][CH3:28])=[O:25])=[CH:22][CH:21]=1)[CH3:18]>>[CH2:1]([O:8][C:9]1[CH:13]=[CH:12][S:11][C:10]=1[C:14]([N:19]([C:20]1[CH:30]=[CH:29][C:23]([C:24]([O:26][CH2:27][CH3:28])=[O:25])=[CH:22][CH:21]=1)[CH2:17][CH3:18])=[O:16])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 170628Benzoic acid, 4-(ethylamino)-, ethyl esterHCID 27667333-(benzyloxy)-2-thiophenecarboxylic acid

Product 1

HCID 22105552HCID 22105552, compound

Procedure

3-Benzyloxy-2-thienylcarboxylic acid was converted to the corresponding acid chloride which was reacted with ethyl 4-ethylaminobenzoate using a similar method to that of Example 4 to give ethyl 4-[N-(3-benzyloxy-2-thienoyl)-N-ethylamino]benzoate.

Sources & evidence

ORD record
ord-95cb6e5120a547fd9fbcd84798ae5531
Source dataset
uspto-grants-1998_12
Patent number
US05843942

Reaction notes

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