HCID 11159460, compound → HCID 22106681, compound

HRID 1456338Notes

Reaction equation

HRID 1456338 reaction equation
[CH3:1][O:2][CH2:3][CH2:4][C:5]1[S:9][CH:8]=[N:7][C:6]=1[CH3:10].[CH3:11][O:12][CH2:13][CH2:14][C:15]1[S:19][C:18]([C:20](=[O:25])[C:21]([F:24])([F:23])[F:22])=[N:17][C:16]=1[CH3:26]>CS(C)=O>[CH3:1][O:2][CH2:3][CH2:4][C:5]1[S:9][C:8]([C:20]([C:18]2[S:19][C:15]([CH2:14][CH2:13][O:12][CH3:11])=[C:16]([CH3:26])[N:17]=2)([OH:25])[C:21]([F:24])([F:23])[F:22])=[N:7][C:6]=1[CH3:10]

Participants

4

Reactant 2

HCID 11159460HCID 11159460, compoundHCID 22106672HCID 22106672, compound

Product 1

HCID 22106681HCID 22106681, compound

Reagents, catalysts & solvents 1

HCID 679Dimethyl SulfoxideSolvent

Procedure

From 5-(2-methoxyethyl)-4-methylthiazole and 5-(2-methoxyethyl)-4-methyl-2-trifluoroacetylthiazole. M.p. 68°-69° C. 13C Nmr (d6 -DMSO) 14.6, 26.0, 57.7, 71.4, 77.0 (q, J 30 Hz), 123.1 (q, J 286 Hz), 131.4, 148.1 and 162.0 ppm.

Sources & evidence

ORD record
ord-dbbf2ef85d1e44f18b99da48aac195b4
Source dataset
uspto-grants-1998_12
Patent number
US05843971

Reaction notes

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