4-Methylthiazole → HCID 22106691, compound
Reaction equation
[CH3:1][C:2]1[N:3]=[CH:4][S:5][CH:6]=1.[F:7][C:8]([F:17])([F:16])[C:9]([C:11]1[S:12][CH:13]=[CH:14][N:15]=1)=[O:10]>>[CH3:1][C:2]1[N:3]=[C:4]([C:9]([C:11]2[S:12][CH:13]=[CH:14][N:15]=2)([OH:10])[C:8]([F:17])([F:16])[F:7])[S:5][CH:6]=1Participants
3
Procedure
From 4-methylthiazole and 2-trifluoroacetylthiazole using the general method of Example 6. M.p. 89°-90° C.
Sources & evidence
- ORD record
- ord-0d2fe65bcbc84870902d1c1f9902309b
- Source dataset
- uspto-grants-1998_12
- Patent number
- US05843971
Reaction notes
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