Methylamine ethanol → HCID 22106155, compound

Participants

Reaction Steps

To a solution of N-[1-butyl-4-{3-(4-phthalimido-1-butynyl)phenyl}-1,2-dihydro-2-oxo-1,8-naphthyridin-3-yl]-N'-(2,6-diisopropylphenyl)urea (50 mg, 0.072 mmol) in ethanol (1 ml) was added 30% methylamine ethanol solution (1.0 ml), and the mixture was stirred at room temperature. The mixture was concentrated under reduced pressure to remove the solvent, and the residue was purified by silica gel column chromatography (5% methanol in chloroform) to give the title compound (33 mg, 0.058 mmol).

Provenance & Evidence