3(S)-(2-((2(S)-Benzoylamino-3-methylbutyryl)benzylamino)acetylamino)-4-(4-(2,6-dichlorophenyl)-oxazol-2-yl)-4-oxobutyric Acid → 3(S)-(2-((2(S)-Benzoylamino-3-methylbutyryl)indan-2-ylamino)acetylamino)-4-(4-(3,5-dichlorophenyl)oxazol-2-yl)-4-oxobutyric Acid

Participants

Reaction Steps

Compound 727 was prepared by a method similar to the method use to prepare compound 710, except compound 704 is replaced with compound 724 in the preparation of compound 708: 1H NMR (500 MHz, CD3OD) δ 8.73 (d), 8.38-8.21 (m), 8.20-8.11 (m), 7.81-7.72 (m), 7.50-7.32 (m), 7.14-6.93 (m), 5.52-5.40 (m), 5.22-5.13 (m), 5.08 (m), 4.96 (d), 4.56 (d), 4.48-4.37 (m), 4.21-4.10 (m), 3.98 (t), 3.82 (d), 3.26-3.11 (m), 3.10-2.88 (m), 2.25-2.12 (m), 1.04-0.83 (m). ##STR106##

Provenance & Evidence