HRID1456675

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID76310

2-Aminoindane

C9H11N

HCID12735618

1,3-Dihydro-2H-isoindol-2-amine

C8H10N2

结构：CC(C)[C@H](NC(=O)c1ccccc1)C(=O)N(CC(=O)N[C@H](C=O)CC(=O)O)Cc1ccccc1

HCID54405243

未命名化合物

PRODUCTS

生成物

结构：CC(C)[C@H](NC(=O)c1ccccc1)C(=O)N(CC(=O)N[C@H](C=O)CC(=O)O)N1Cc2ccccc2C1

HCID54120604

未命名化合物

PROCEDURE

实验过程

Compound 756 was prepared by a method similar to the method used to prepare compound 724 and compound 706, except 2-aminoindane was replaced with 2-aminoisoindoline (prepared as described in Eloy, F., Moussebois, C., Bull. Soc. Chim. Belg., 68, pp. 409-421 (1959)). ##STR136##

WORKUP

后处理

customprepared

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-bf7c302022864f00923a0985f670be93
来源数据集: uspto-grants-1998_12
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05843904
来源说明: uspto-grants-1998_12

反应 SMILES

[C:1]([NH:9][C@@H:10]([CH:32]([CH3:34])[CH3:33])[C:11]([N:13](CC1C=CC=CC=1)[CH2:14][C:15]([NH:17][C@H:18]([CH:23]=[O:24])[CH2:19][C:20]([OH:22])=[O:21])=[O:16])=[O:12])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.NC1CC2C(=CC=CC=2)C1.N[N:46]1[CH2:54][C:53]2[C:48](=[CH:49][CH:50]=[CH:51][CH:52]=2)[CH2:47]1>>[C:1]([NH:9][C@@H:10]([CH:32]([CH3:33])[CH3:34])[C:11]([N:13]([N:46]1[CH2:54][C:53]2[C:48](=[CH:49][CH:50]=[CH:51][CH:52]=2)[CH2:47]1)[CH2:14][C:15]([NH:17][C@H:18]([CH:23]=[O:24])[CH2:19][C:20]([OH:22])=[O:21])=[O:16])=[O:12])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1