Phenoxyacetic Acid → Phenoxyacetyl chloride

HRID 1456875Notes

Reaction equation

HRID 1456875 reaction equation
[O:1]([CH2:8][C:9]([OH:11])=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.S(Cl)([Cl:14])=O>>[O:1]([CH2:8][C:9]([Cl:14])=[O:11])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 19188Phenoxyacetic AcidHCID 24386Thionyl Chloride

Product 1

HCID 69703Phenoxyacetyl chloride

Procedure

Phenoxyacetic acid (d5) was treated with 25 ml of thionyl chloride and stirred for 18 hours at room temperature. After the end of the reaction, the reaction mixture was concentrated under vacuum at 30° C. to provide phenoxyacetyl chloride (4.8 g).

Workup

  1. customAfter the end of the reaction
  2. concentrationthe reaction mixture was concentrated under vacuum at 30° C.

Sources & evidence

ORD record
ord-3cb2d5ba282249be8aafc22f7d3e0c65
Source dataset
uspto-grants-1998_12
Patent number
US05846514

Reaction notes

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