Acetone → 4-Ethynylphenol

Participants

Reaction Steps

50.0 g of the resin synthesized in Reference Example 1 was dissolved in 500 ml of acetone. After adding 4.8 g of potassium carbonate, 0.96 g of potassium iodide and 5.0 g of tert-butylchloroacetate, the solution obtained was refluxed for 10 hours. After filtration of the reaction solution, 1 l of methylisobutylketone was mixed to the resin solution thus obtained, and the resulting solution was washed three times with 500 ml of ion-exchange water. The methylisobutylketone was distilled out under reduced pressure to obtain hydrogenated poly(p-vinylphenol), wherein 12% of the hydroxyl groups were ethyletherified and 8% of the hydroxyl groups were tert-butoxycarbonylmethyletherified.

Provenance & Evidence