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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1456946Generated: October 30, 2026

4,6-Dichloro-2-(methylthio)-5-nitropyrimidine → 2-Methylthio-4-chloro-5-nitro-6-(2-benzyloxy-5-cyanophenoxy)pyrimidine

https://huagongshe.com/reaction/1456946

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4,6-Dichloro-2-(methylthio)-5-nitropyrimidineHCID 11345458—
Reactant4-(Benzyloxy)-3-hydroxybenzonitrileHCID 15453451—
Product2-Methylthio-4-chloro-5-nitro-6-(2-benzyloxy-5-cyanophenoxy)pyrimidineHCID 22102986—

Reaction Steps

In a similar manner, 2-methylthio-4,6-dichloro-5-nitropyrimidine, a compound of formula (A), was treated with 2-benzyloxy-5-cyanophenol to yield 2-methylthio-4-chloro-5-nitro-6-(2-benzyloxy-5-cyanophenoxy)pyrimidine, a compound of formula (K).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05846970
Source datasetuspto-grants-1998_12
ORD IDord-8a42cf80e7a940f5babe5c4001fa1304
Source noteuspto-grants-1998_12