HuagongsheHuagongshe Chemistry Print Report · For research reference only
Glycine ethyl ester, hydrochloride → 2-Methylthio-4-(ethoxycarbonylmethyl)amino-5-nitro-6-(2-benzyloxy-5-cyanophenoxy)pyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Glycine ethyl ester, hydrochloride | HCID 2723640 | — |
| Reactant | 2-Methylthio-4-chloro-5-nitro-6-(2-benzyloxy-5-cyanophenoxy)pyrimidine | HCID 22102986 | — |
| Product | 2-Methylthio-4-(ethoxycarbonylmethyl)amino-5-nitro-6-(2-benzyloxy-5-cyanophenoxy)pyrimidine | HCID 22103040 | — |
Reaction Steps
In a similar manner, 2-methylthio-4-chloro-5-nitro-6-(2-benzyloxy-5-cyanophenoxy)pyrimidine, a compound of formula (K), is treated with glycine ethyl ester hydrochloride, a compound of formula (D), to yield 2-methylthio-4-(ethoxycarbonylmethyl)amino-5-nitro-6-(2-benzyloxy-5-cyanophenoxy)pyrimidine, a compound of formula (L).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05846972 |
| Source dataset | uspto-grants-1998_12 |
| ORD ID | ord-4038d133a86b43afa422750d7958d087 |
| Source note | uspto-grants-1998_12 |