HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Methyl-4-piperidone → 6-fluoro-3-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Methyl-4-piperidone | HCID 74049 | — |
| Reactant | 6-Fluoroindole | HCID 351278 | — |
| Product | 6-fluoro-3-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-indole | HCID 18797305 | 70% |
Reaction Steps
Beginning with 1.00 gm (7.4 mMol) 6-fluoro-1H-indole and 1.82 mL (14.8 mMol) 1-methyl-4-piperidone, 1.18 gm (70%) of the title compound were recovered as a colorless crystalline solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05846982 |
| Source dataset | uspto-grants-1998_12 |
| ORD ID | ord-7b9f0eb299e84388b9f1e7c73933e829 |
| Source note | uspto-grants-1998_12 |