HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Methyl-4-piperidone → 7-chloro-3-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Methyl-4-piperidone | HCID 74049 | — |
| Reactant | 7-chloro-1H-indole | HCID 104644 | — |
| Product | 7-chloro-3-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-indole | HCID 18797235 | 81.1% |
Reaction Steps
Beginning with 0.50 gm (3.3 mMol) 7-chloro-1H-indole and 0.81 mL (6.6 mMol) 1-methyl-4-piperidone, 0.66 gm (81%) of the title compound were recovered as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05846982 |
| Source dataset | uspto-grants-1998_12 |
| ORD ID | ord-31199bbac13b4780b9179fb898e807c9 |
| Source note | uspto-grants-1998_12 |