1-Methyl-4-piperidone → HCID 18797484, compound

HRID 1456975Notes

Reaction equation

HRID 1456975 reaction equation
[N+:1]([C:4]1[CH:12]=[C:11]2[C:7]([CH:8]=[CH:9][NH:10]2)=[CH:6][CH:5]=1)([O-:3])=[O:2].[CH3:13][N:14]1[CH2:19][CH2:18][C:17](=O)[CH2:16][CH2:15]1>>[N+:1]([C:4]1[CH:12]=[C:11]2[C:7]([C:8]([C:17]3[CH2:18][CH2:19][N:14]([CH3:13])[CH2:15][CH:16]=3)=[CH:9][NH:10]2)=[CH:6][CH:5]=1)([O-:3])=[O:2]

Participants

3

Reactant 2

HCID 740491-Methyl-4-piperidoneHCID 785026-Nitro-1H-indole

Product 1

HCID 18797484HCID 18797484, compoundYield 81.2%

Procedure

Beginning with 2.00 gm (12.3 mMol) 6-nitro-1H-indole and 3.00 mL (24.7 mMol) 1-methyl-4-piperidone, 2.57 gm (81%) of the title compound were recovered as a yellow solid.

Sources & evidence

ORD record
ord-3c20975f53a748f7bfeac691904a6345
Source dataset
uspto-grants-1998_12
Patent number
US05846982

Reaction notes

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