1-Methyl-4-piperidone → HCID 18797306, compound

HRID 1456976Notes

Reaction equation

HRID 1456976 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][C:10]=1[Cl:11])[NH:7][CH:6]=[CH:5]2.[CH3:12][N:13]1[CH2:18][CH2:17][C:16](=O)[CH2:15][CH2:14]1>>[Cl:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][C:10]=1[Cl:11])[NH:7][CH:6]=[C:5]2[C:16]1[CH2:17][CH2:18][N:13]([CH3:12])[CH2:14][CH:15]=1

Participants

3

Reactant 2

HCID 740491-Methyl-4-piperidoneHCID 104877765,6-dichloro-1H-indole

Product 1

HCID 18797306HCID 18797306, compoundYield 61%

Procedure

Beginning with 0.136 gm (0.88 mMol) 5,6-dichloro-1H-indole and 0.216 mL (1.75 mMol) 1-methyl-4-piperidone, 0.150 gm (61%) of the title compound were recovered as a white solid.

Sources & evidence

ORD record
ord-ddef82a428f74fca9233b36e00ff9255
Source dataset
uspto-grants-1998_12
Patent number
US05846982

Reaction notes

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