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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1456977Generated: October 25, 2026

1-Methyl-4-piperidone → 6,7-dichloro-3-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-indole

https://huagongshe.com/reaction/1456977

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Methyl-4-piperidoneHCID 74049—
Reactant6,7-dichloro-1H-indoleHCID 12272802—
Product6,7-dichloro-3-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-indoleHCID 1879740995%

Reaction Steps

Beginning with 0.50 gm (2.7 mMol) 6,7-dichloro-1H-indole and 0.66 mL (5.4 mMol) 1-methyl-4-piperidone, 0.72 gm (95%) of the title compound were recovered as a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05846982
Source datasetuspto-grants-1998_12
ORD IDord-bdd05447f75f48439aabb0ef1717fba1
Source noteuspto-grants-1998_12