HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Chloroindole → 6-chloro-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Chloroindole | HCID 87111 | — |
| Reactant | Piperonylamine | HCID 2723901 | — |
| Product | 6-chloro-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole | HCID 10059854 | 61.2% |
Reaction Steps
Beginning with 4.0 gm (26.0 mMol) 6-chloro-1H-indole and 8.0 gm (52.0 mMol) 4-piperidone hydrochloride monohydrate, 3.7 gm (61%) of the title compound were recovered as a yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05846982 |
| Source dataset | uspto-grants-1998_12 |
| ORD ID | ord-93c3b52e7c704f09a1b3bc567f4f03ce |
| Source note | uspto-grants-1998_12 |