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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1456990Generated: November 3, 2026

5-Methoxyindole → 5-Methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1H indole

https://huagongshe.com/reaction/1456990

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-MethoxyindoleHCID 13872—
ReactantPiperonylamineHCID 2723901—
Product5-Methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1H indoleHCID 10802979%

Reaction Steps

Beginning with 5.0 gm (34.0 mMol) 5-methoxy-1H-indole and 10.0 gm (65.0 mMol) 4-piperidone hydrochloride monohydrate, 6.1 gm (79%) of the title compound were recovered as a yellow solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05846982
Source datasetuspto-grants-1998_12
ORD IDord-4f3109ba248b4c00acff8c540701eb43
Source noteuspto-grants-1998_12