Pyridine-4-carbonyl chloride → HCID 15428633, compound

HRID 1457062Notes

Reaction equation

HRID 1457062 reaction equation
[CH3:1][N:2]([CH3:17])[CH:3]1[CH2:16][CH2:15][C:6]2[O:7][C:8]3[CH:13]=[CH:12][C:11]([NH2:14])=[CH:10][C:9]=3[C:5]=2[CH2:4]1.[C:18](Cl)(=[O:25])[C:19]1[CH:24]=[CH:23][N:22]=[CH:21][CH:20]=1>>[CH3:1][N:2]([CH3:17])[CH:3]1[CH2:16][CH2:15][C:6]2[O:7][C:8]3[CH:13]=[CH:12][C:11]([NH:14][C:18]([C:19]4[CH:24]=[CH:23][N:22]=[CH:21][CH:20]=4)=[O:25])=[CH:10][C:9]=3[C:5]=2[CH2:4]1

Participants

3

Reactant 2

HCID 417436Pyridine-4-carbonyl chlorideHCID 9839408HCID 9839408, compound

Product 1

HCID 15428633HCID 15428633, compoundYield 42.4%

Procedure

Beginning with 0.132 gm (0.57 mMol) of N,N-dimethyl-8-amino-1,2,3,4-tetrahydro-2-dibenzofuranamine and 0.15 gm (0.84 mMol) of isonicotinoyl chloride, 0.081 gm (42%) of the title compound were obtained by the procedure described in Example 20.

Sources & evidence

ORD record
ord-c49ddab549f14da7b55600f658b6c343
Source dataset
uspto-grants-1998_12
Patent number
US05846995

Reaction notes

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