Cyclopropylamine → HCID 21221737, compound

HRID 1457077Notes

Reaction equation

HRID 1457077 reaction equation
[CH3:1][N:2]([CH3:19])[CH:3]1[CH2:18][CH2:17][C:6]2[O:7][C:8]3[CH:13]=[CH:12][C:11]([C:14](Cl)=[O:15])=[CH:10][C:9]=3[C:5]=2[CH2:4]1.[CH:20]1([NH2:23])[CH2:22][CH2:21]1>>[CH:20]1([NH:23][C:14]([C:11]2[CH:12]=[CH:13][C:8]3[O:7][C:6]4[CH2:17][CH2:18][CH:3]([N:2]([CH3:19])[CH3:1])[CH2:4][C:5]=4[C:9]=3[CH:10]=2)=[O:15])[CH2:22][CH2:21]1

Participants

3

Reactant 2

HCID 69828CyclopropylamineHCID 21221671HCID 21221671, compound

Product 1

HCID 21221737HCID 21221737, compoundYield 33.5%

Procedure

Beginning with 0.011 gm (0.04 mMol) 2-dimethylamino-1,2,3,4-tetrahydrodibenzofuran-8-carbonyl chloride and 0.08 mMol cyclopropylamine, 0.004 gm (32%) of the title compound were recovered.

Sources & evidence

ORD record
ord-d3ddbda9f18a46fc8df235c0f3b1e23b
Source dataset
uspto-grants-1998_12
Patent number
US05846995

Reaction notes

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