HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → 2-Bromo-5-(2-oxazolyl)benzeneacetyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | 2-Bromo-5-(2-oxazolyl)benzeneacetic acid | HCID 22103739 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 2-Bromo-5-(2-oxazolyl)benzeneacetyl chloride | HCID 22103504 | — |
Reaction Steps
To the title compound of Step (B) and 0.048 ml dimethylformamide (DMF) in 19 ml CH2Cl2, oxalyl chloride (2M in CH2Cl2, 2.38 ml, 4.75 mmol) was added. The reaction was stirred at room temperature for 1 hour and concentrated to give the title compound of this step as a gum.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05846990 |
| Source dataset | uspto-grants-1998_12 |
| ORD ID | ord-22120d8aaa6b419794a989583b536f0d |
| Source note | uspto-grants-1998_12 |