Sulfamic Acid → HCID 22103717, compound

Participants

Reaction Conditions

Reaction Steps

To the title compound of Step (B) (300 mg, 0.57 mmol) and H2NSO3H (111 mg, 1.14 mmol) in 11.4 ml THF at 0° C., an ice cooled solution of NaClO2 (103 mg, 1.14 mmol) in 11.4 ml H2O was added. The mixture was stirred at 0° C. for 2 min. 60 ml CH2 Cl2 was added. The organic layer was separated and washed with H2O and brine, dried and concentrated to afford the title compound of this step, which was relatively pure and was used in the next step without further purification.

Provenance & Evidence