HCID 53677988, compound → HCID 54552132, compound

Participants

Reaction Steps

N-t-Butyloxycarbonyl β-benzyl-L-aspartic acid allyl ester (3-1) (2.95 g; 8.11 mmol) was stirred in trifluoracetic acid (30 ml) at room temperature for 45 min. The solvent was removed in vacuo and the residue evaporated from ether (30 ml×2). The resultant yellow oil was dissolved in DCM (40 ml), washed with saturated sodium bicarbonate solution (30 ml), brine (30 ml×2) and dried (sodium sulphate). Filtration and evaporation of the solvent gave the product as a yellow oil which was used without further purification.

Provenance & Evidence