Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | (+-)-Methionine | HCID 876 | — |
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | HCID 86753422 | HCID 86753422 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 86753421 | HCID 86753421 | 200.8% |
Reaction Steps
A 50 ml capacity glass reaction flask was charged with 5 g (33.56 mmol) of DL-methionine, 30.20 g (302.04 mmol) of concentrated sulfuric acid and 16.4 g of water and then the contents were heated under reflux for 3.5 hours at 135° C. in a stream of nitrogen. The reaction solution was analyzed by liquid chromatography. As a result, it was found that 2.92 g (7.97 mmol) of DL-homocystine sulfate and 4.96 g (16.00 mmol) of DL-methionine-S-methylsulfonium sulfate were formed. The conversion ratio was 100% and the selectivity was 48%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US05847205 |
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| Source dataset | uspto-grants-1998_12 |
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| ORD ID | ord-dd4851b86cd4402f9d605fb594c7ce3b |
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| Source note | uspto-grants-1998_12 |
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