p-Toluenesulfonic acid → HCID 22099459, compound

Participants

Reaction Steps

Ethyl acetate (4 ml) was added to 100 mg of 2-[3-(4-pyridylmethyl)-3-(3-pyridyl)ureido]-4-methoxy-6-tert-butylphenol and the mixture was heated. 94 mg of p-toluenesulfonic acid was added to the above solution. After cooling the solution, the solvent was removed under reduced pressure and the residue was crystallized from an ethanol solution to give 129 mg of 2-[3-(4-pyridylmethyl)-3-(3-pyridyl)ureido]-4-methoxy-6-tert-butylphenol di-p-toluenesulfonate (yield: 70%, melting point: 124°-128 C.).

Provenance & Evidence