HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triphosgene → {2-[3-Phenyl-3-(4-benzyloxycarbonylaminocyclohexyl)ureido]-4-methoxy-6-tert-butylphenoxy}methoxymethane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triphosgene | HCID 94429 | — |
| Reactant | (2-Amino-4-methoxy-6-tert-butylphenoxy)methoxymethane | HCID 18765846 | — |
| Reactant | N-phenyl-N-(4-benzyloxycarbonylaminocyclohexyl)amine | HCID 22099404 | — |
| Product | {2-[3-Phenyl-3-(4-benzyloxycarbonylaminocyclohexyl)ureido]-4-methoxy-6-tert-butylphenoxy}methoxymethane | HCID 22099492 | — |
Reaction Steps
(2-Amino-4-methoxy-6-tert-butylphenoxy)methoxymethane, N-phenyl-N-(4-benzyloxycarbonylaminocyclohexyl)amine and triphosgene were treated in the same manner as described in Example 53 to give {2-[3-phenyl-3-(4-benzyloxycarbonylaminocyclohexyl)ureido]-4-methoxy-6-tert-butylphenoxy}methoxymethane (melting point: 145°-154° C.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05849732 |
| Source dataset | uspto-grants-1998_12 |
| ORD ID | ord-6e52bb51aa36434294bca84bd6829e28 |
| Source note | uspto-grants-1998_12 |