Aniline → N-phenyl-N-(4-benzyloxycarbonylaminocyclohexyl)amine

HRID 1457600Notes

Reaction equation

HRID 1457600 reaction equation
[CH2:1]([O:8][C:9]([NH:11][CH:12]1[CH2:17][CH2:16][C:15](=O)[CH2:14][CH2:13]1)=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[NH2:19][C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1>>[CH2:1]([O:8][C:9]([NH:11][CH:12]1[CH2:17][CH2:16][CH:15]([NH:19][C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)[CH2:14][CH2:13]1)=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 6115AnilineHCID 14615292Benzyl (4-oxocyclohexyl)carbamate

Product 1

HCID 22099404N-phenyl-N-(4-benzyloxycarbonylaminocyclohexyl)amine

Procedure

N-benzyloxycarbonyl-4-aminocyclohexanone and aniline were treated in the same manner as described in Reference example 51 to give N-benzyloxycarbonyl-N'-phenyl-1,4-diaminocyclohexane.

Sources & evidence

ORD record
ord-da14d2ef6f904fe4aa501355ce5233ea
Source dataset
uspto-grants-1998_12
Patent number
US05849732

Reaction notes

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