Triethylamine → HCID 22100392, compound

Participants

Reaction Conditions

Reaction Steps

4.8 g(0.01197 mole) of the compound obtained in step 7, 3.75 g(0.03591 mole) of phenylboric acid, 0.2 g(0.0012 mole) of palladium acetate, 0.46 g(0.0024 mole) of triphenylphosphine and 8.9 ml(0.0838 mole) of triethylamine were dissolved in 20 ml of dimethyl formamide. The reaction solution was stirred for 3 hours at 120° C., diluted with 100 ml of ethyl acetate and washed with water(50 ml×3). The organic layer was dried over Na2SO4 and concentrated under reduced pressure. The residue was purified with column chromatography(5% MeOH in CH2 Cl2) to obtain 4.57 g of the title compound(yield 96%).

Provenance & Evidence