1,1-Dimethyl-2-(3-pyridylmethyl)hydrazine → S-methyl-N-(6-chloro-3-pyridylmethyl)-N-methyl-N'-methylisothiourea

HRID 1457894Notes

Reaction equation

HRID 1457894 reaction equation
[Cl:1][C:2]1[N:7]=[CH:6][C:5]([CH2:8][N:9]([CH3:14])[C:10]([NH:12][CH3:13])=[S:11])=[CH:4][CH:3]=1.[CH3:15]N(C)NCC1C=NC=CC=1.ClC1C(CN)=CC=C(Cl)N=1>>[CH3:15][S:11][C:10](=[N:12][CH3:13])[N:9]([CH2:8][C:5]1[CH:6]=[N:7][C:2]([Cl:1])=[CH:3][CH:4]=1)[CH3:14]

Participants

4

Reactant 3

HCID 111481501,1-Dimethyl-2-(3-pyridylmethyl)hydrazineHCID 150289211-(6-Chloro-3-pyridylmethyl)-1,3-dimethylthioureaHCID 15477284(2,6-Dichloropyridin-3-YL)methanamine

Product 1

HCID 22450313S-methyl-N-(6-chloro-3-pyridylmethyl)-N-methyl-N'-methylisothiourea

Procedure

Using the N-(6-chloro-3-pyridylmethyl)-N-methyl-N'-methylthiourea otained in (1), the procedure of Example 8 (2) was repeated to give S-methyl-N-(6-chloro-3-pyridylmethyl)-N-methyl-N'-methylisothiourea as oil.

Sources & evidence

ORD record
ord-2452e45e7eb14672bf95fdc0bb799385
Source dataset
uspto-grants-1998_12
Patent number
US05849768

Reaction notes

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