Hydrochloric Acid → HCID 214553, compound

Participants

Reaction Conditions

Reaction Steps

N-(2,3-Dihydro-1H-phenalen-2-yl)acetamide (0.97 mmol; 0.22 g) is solubilized in 2 cm3 of dioxane and 9 cm3 of 10% HCl are added. The mixture is maintained at 100° C. for 3 h and then at 90° C. overnight. After cooling, 10% NaOH is added until the pH is basic and the amine is extracted with CH2Cl2. The organic phase is dried over MgSO4 and evaporated under reduced pressure. The desired amine is thus isolated without further purification.

Provenance & Evidence