HCID 9795630, compound → 2,4,5-Trifluoro-3-methylbenzoic acid

HRID 1457968Notes

Reaction equation

HRID 1457968 reaction equation
C([CH2:4][C:5]1[C:6]([F:19])=[C:7]([C:16]([OH:18])=[O:17])[C:8](=[C:12]([F:15])[C:13]=1[F:14])C(O)=O)(O)=O>CS(C)=O>[CH3:4][C:5]1[C:6]([F:19])=[C:7]([CH:8]=[C:12]([F:15])[C:13]=1[F:14])[C:16]([OH:18])=[O:17]

Participants

3

Reactant 1

HCID 9795630HCID 9795630, compound

Product 1

HCID 118055142,4,5-Trifluoro-3-methylbenzoic acid

Reagents, catalysts & solvents 1

HCID 679Dimethyl SulfoxideSolvent

Procedure

The thus obtained 4-carboxymethyl-3,5,6-trifluorophthalic acid is heated in dimethyl sulfoxide in the presence of a base to give 3-methyl-2,4,5-trifluorobenzoic acid.

Sources & evidence

ORD record
ord-5e8d0122e3e5426e90a974b1787e9643
Source dataset
uspto-grants-1998_12
Patent number
US05849757

Reaction notes

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