反应详情

A 525 mg (1.59 mmol) portion of 1-benzyl-3-(1-tert-butoxycarbonylaminocyclobutyl)pyrrolidine (fr. 2) was dissolved in 50.0 ml of ethanol, mixed with 500 mg of 10% palladium-carbon and stirred for 3 hours under a hydrogen pressure of 4 atm with warming by an infrared lamp. After removing the catalyst by filtration, the solvent was evaporated to yield quantitative amount of the title compound.

1. temperaturewith warming by an infrared lamp
2. customAfter removing the catalyst
3. filtrationby filtration
4. customthe solvent was evaporated