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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1458234Generated: October 25, 2026

Ammonia → 2-Amino-3,6-dichloro-5-trifluoromethylpyridine

https://huagongshe.com/reaction/1458234

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmmoniaHCID 222—
Reactant2,5-Dichloro-6-methoxy-3-trifluoromethylpyridineHCID 18689510—
Product2-Amino-3,6-dichloro-5-trifluoromethylpyridineHCID 13064154—

Reaction Steps

If, in contrast, the novel 2,5-dichloro-6-methoxy-3-trifluoromethylpyridine is reacted with ammonia, the undesired 2-amino-3,6-dichloro-5-trifluoromethylpyridine is predominantly formed while the methoxy group is lost.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05849920
Source datasetuspto-grants-1998_12
ORD IDord-112454546d924247a77b9ceb5f6006c8
Source noteuspto-grants-1998_12