HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic acid, 2-(triphenylphosphoranylidene)-, methyl ester → HCID 178499690, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic acid, 2-(triphenylphosphoranylidene)-, methyl ester | HCID 17453 | — |
| Reactant | HCID 178418743 | HCID 178418743 | — |
| Product | HCID 178499690 | HCID 178499690 | 74.3% |
Reaction Steps
To a solution of 1H-benzoimidazole-5-carboxaldehyde (250 mg in 12 mL dry tetrahydrofuran) at 0° C. was added 1.43 g methyl(triphenylphosphoranylidene)acetate and the mixture allowed to warm to room temperature. After 24 hours the mixture was concentrated in vacuo and purified by flash chromatography on silica gel (methylene chloride:methanol, 93:7) to give the title compound (257 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05849764 |
| Source dataset | uspto-grants-1998_12 |
| ORD ID | ord-30a3e8d15b3a4dc9bc79539ff20fa1b5 |
| Source note | uspto-grants-1998_12 |