反应详情

To a solution of 3-pyridin-3-yl-cyclohex-2-enone (1.25 g in 50 mL ethanol) was added 164 mg of platinum oxide catalyst and the mixture subjected to hydrogen at 40 psi. After 2 hours, the catalyst was removed by filtration and the filtrate concentrated in vacuo. Purification of the residue by flash chromatography on silica gel (ethyl acetate:hexane, 1:1) gave the title compound (427 mg).

1. customthe catalyst was removed by filtration
2. concentrationthe filtrate concentrated in vacuo
3. customPurification of the residue by flash chromatography on silica gel (ethyl acetate:hexane, 1:1)