HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Indole-3-Carboxylic Acid → (1-Benzyl-4-piperidyl)methyl indole-3-carboxylate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Indole-3-Carboxylic Acid | HCID 69867 | — |
| Edukt | (1-Benzylpiperidin-4-yl)methanol | HCID 736802 | — |
| Produkt | (1-Benzyl-4-piperidyl)methyl indole-3-carboxylate | HCID 19599412 | 88% |
Reaktionsschritte
Indole-3-carboxylic acid was converted to its acid chloride and then reacted with 1-benzyl-4-piperidinemethanol (D7) using the method given in Example 1a. The resulting orange oil was chromatographed on silica gel eluting with chloroform/ethanol (9:1) to afford (1-benzyl-4-piperidyl)methyl indole-3-carboxylate as a yellow oil (88%).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05852014 |
| Quelldatensatz | uspto-grants-1998_12 |
| ORD ID | ord-f803b1fddf174cc78f067da1fe213c9a |
| Quellennotiz | uspto-grants-1998_12 |