HuagongsheHuagongshe Chemistry Print Report · For research reference only
Indole-3-Carboxylic Acid → N-[(l-benzyl-4-piperidyl)methyl] indole-3-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Indole-3-Carboxylic Acid | HCID 69867 | — |
| Reactant | (1-Benzyl-4-piperidyl)methanamine | HCID 1514444 | — |
| Product | N-[(l-benzyl-4-piperidyl)methyl] indole-3-carboxamide | HCID 19599446 | 60% |
Reaction Steps
Indole-3-carboxylic acid was converted to its acid chloride and then reacted with (1-benzyl-4-piperidyl)methylamine (D10) as in the method of Description 1b to afford N-[(1-benzyl-4-piperidyl)methyl] indole-3-carboxamide as a white solid (60%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05852014 |
| Source dataset | uspto-grants-1998_12 |
| ORD ID | ord-aaa906566cef4605af0ff2d0a1c74d35 |
| Source note | uspto-grants-1998_12 |