HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thiazolo[3,2-a]indole-9-carboxylic acid → Quinolizidin-2-ylmethyl thiazolo[3,2-a]indole-9-Carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thiazolo[3,2-a]indole-9-carboxylic acid | HCID 19599418 | — |
| Reactant | Octahydro-2H-quinolizine-2-methanol | HCID 70077295 | — |
| Product | Quinolizidin-2-ylmethyl thiazolo[3,2-a]indole-9-Carboxylate | HCID 131720987 | — |
Reaction Steps
Thiazolo[3,2-a]indole-9-carboxylic acid (D16) was converted to its acid chloride and reacted with eq-2-hydroxymethylquinolizidine using a procedure analogous to that described in Example 10 to afford the title compound as a white solid mp 129°-131° C. (ether).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05852014 |
| Source dataset | uspto-grants-1998_12 |
| ORD ID | ord-5300f6a31d6442eea4ccbc3f9daa3cba |
| Source note | uspto-grants-1998_12 |