HCID 12299017, compound → Benzoic acid, 4-[[bis(2-chloroethyl)amino]methyl]-

Participants

Reaction Steps

Concentrated hydrochloric acid (50 ml) was added to 9.5 g (32.7 mmol) of methyl 4-[N,N-bis(2-chloroethyl)aminomethyl]benzoate, followed by stirring under heating and reflux for 2 hours. After the solvent was distilled out under reduced pressure, the residue was washed with acetone, whereby 8.5 g of white powder were obtained.

Provenance & Evidence