Dichloromethane → HCID 22096864, compound

Participants

Reaction Steps

Thionyl chloride (0.8 ml; 11.0 mmol) was added to a solution of 1.0 g (4.0 mmol) of ethyl 2-[N,N-bis(2-hydroxyethyl)amino]benzoate in 5 ml of methylene chloride, followed by stirring at room temperature for 1 hour. After the solvent was distilled out under reduced pressure, methylene chloride was added again in a small amount and was then distilled out under reduced pressure. This procedure was repeated twice. The resultant mixture was concentrated under reduced pressure, whereby 950 mg of a brown oil were obtained (yield: 83%).

Provenance & Evidence