Dichloromethane → HCID 22096808, compound

Participants

Reaction Steps

Thionyl chloride (0.7 ml; 9.6 mmol) was added to a solution of 1.0 g (3.7 mmol) of methyl 3-methoxy-4-[bis(2-hydroxyethyl)amino]benzoate in 20 ml of methylene chloride, followed by stirring at room temperature for 3 hours. After the solvent was distilled out under reduced pressure, methylene chloride was added again in a small amount and was then distilled out under reduced pressure. This procedure was repeated twice. The resultant mixture was evaporated to dryness under reduced pressure, whereby 1.0 g of a brown oil was obtained (yield: 88%).

Provenance & Evidence