Thionyl Chloride → HCID 22096790, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 3.0 g (14.3 mmol) of 4-[N-ethyl,N-(2-hydroxyethyl)amino]nitrobenzene in 20 ml of chloroform, 2.1 ml (28.8 mmol) of thionyl chloride were added. After the resultant mixture was stirred under heat at 80° C. for 2 hours, the solvent was distilled out under reduced pressure. The residue was purified by chromatography on a silica gel column (ethyl acetate/n-hexane=1/1), whereby 3.0 g of yellow powder were obtained (yield: 92%).

Provenance & Evidence