Tin tetrachloride → HCID 22096897, compound

Participants

Reaction Steps

To a solution of 3.0 g (13.1 mmol) of 4-[N-ethyl,N-(2-chloroethyl)amino]nitrobenzene in 70 ml of a concentrated hydrochloric acid, 10 g of tin chloride were added. The resultant mixture was refluxed under heat for 3 hours, followed by treatment with aqueous ammonia and extraction with chloroform. The solvent was distilled out under reduced pressure. A solution of 4N hydrochloric acid/dioxane was added to the residue, followed by washing with IPA, whereby 3.1 g of the powder were obtained (yield: 100%).

Provenance & Evidence