2,5-Dimethoxytetrahydrofuran → HCID 22097215, compound

HRID 1458791Notes

Reaction equation

HRID 1458791 reaction equation
[C:1]([NH:4][C:5]1[C:10]([NH:11][C:12](=[O:14])[CH3:13])=[CH:9][C:8]([Cl:15])=[C:7]([NH2:16])[CH:6]=1)(=[O:3])[CH3:2].CO[CH:19]1[CH2:23][CH2:22][CH:21](OC)O1>C(O)(=O)C>[Cl:15][C:8]1[CH:9]=[C:10]([NH:11][C:12](=[O:14])[CH3:13])[C:5]([NH:4][C:1](=[O:3])[CH3:2])=[CH:6][C:7]=1[N:16]1[CH:19]=[CH:23][CH:22]=[CH:21]1

Participants

4

Reactant 2

HCID 790982,5-DimethoxytetrahydrofuranHCID 22097164HCID 22097164, compound

Product 1

HCID 22097215HCID 22097215, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

3 g (12.4 mmol) of 4,5-diacetamido-2-amino-1-chlorobenzene and 1.6 g (12.4 mmol) of 2,5-dimethoxytetrahydrofuran in 150 ml of acetic acid were refluxed for 30 minutes. The reaction mixture was concentrated, the residue was washed with water and ethyl acetate, and the organic phase was worked up.

Workup

  1. concentrationThe reaction mixture was concentrated
  2. washthe residue was washed with water and ethyl acetate

Sources & evidence

ORD record
ord-76824db84d494025b46decdad75e71dd
Source dataset
uspto-grants-1998_12
Patent number
US05852017

Reaction notes

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