Dehydrocavidine dehydroapocavidine → Dehydroisoapocavidine

Participants

Reaction Steps

200 mg of the dehydrocavidine-dehydroapocavidine composition obtained from the above step is dissolved with 10 ml of methanol, and are then loaded to the top of the sephadex gel column, and a gradient elution is employed with 30%˜70% methanol, accompanied by TLC tracking. The eluate containing dehydrocavidine is combined and is then concentrated by decompression to a constant weight, resulting in obtaining 22 mg of a dehydrocavidine compound and 14 mg of a dehydroapocavidine compound respectively.

Provenance & Evidence