Nitric Acid → 6-Bromo-2-methoxy-1-nitronaphthalene

HRID 1458854노트

반응식

HRID 1458854 반응식
[N+:1]([O-:4])(O)=[O:2].[Br:5][C:6]1[CH:7]=[C:8]2[C:13](=[CH:14][CH:15]=1)[CH:12]=[C:11]([O:16][CH3:17])[CH:10]=[CH:9]2>C(O)(=O)C>[Br:5][C:6]1[CH:7]=[C:8]2[C:13](=[CH:14][CH:15]=1)[C:12]([N+:1]([O-:4])=[O:2])=[C:11]([O:16][CH3:17])[CH:10]=[CH:9]2

참가 물질

4

반응물 2

HCID 944Nitric AcidHCID 787862-Bromo-6-methoxynaphthalene

생성물 1

HCID 220971876-Bromo-2-methoxy-1-nitronaphthalene수율 90%

시약·촉매·용매 1

HCID 176Acetic Acid용매2회

반응 조건

온도
50 °C

실험 절차

10 ml of 98% strength nitric acid dissolved in 70 ml of acetic acid were added dropwise to 50 g (0.21 mol) of 6-bromo-2-methoxynaphthalene dissolved in 350 ml of acetic acid at room temperature. The mixture was heated to 50° C. and, after the product had crystallized, cooled. The precipitate was filtered off with suction to yield 53.1 g (90%) of the product. Melting point 156°-157° C.

후처리

  1. customafter the product had crystallized
  2. temperaturecooled
  3. filtrationThe precipitate was filtered off with suction

출처 및 근거

ORD 기록
ord-07abfbe85df24df695b3b3d7f7fdd1d5
출처 데이터셋
uspto-grants-1998_12
특허 번호
US05852017

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